He was also personally involved in the construction of the new headquarters for the Institute in 1892, in 1905 he founded the Asilo Infantile per ciechi (Kindergarten for the Blind) in 1915 he opened the Laboratorio Zirotti, together with Pietro Stoppani, for the professional training of blind soldiers returning from the war.
In parallel with his commitments to the welfare and education of the blind, Vitali did not set aside his political interests and his liberal ideas, as shown by the article he wrote for the “Rassegna Nazionale” in 1894.
Towards the end of his years, having completed his commitments in Milan, he decided to retire to the lands of Alto Lario where he had great influence on the local social and cultural life, without ceasing to do his best for the less fortunate: in fact, he sensitized prominent local personalities who made important donations with the sole aim of improving the living conditions of the less fortunate. In Bellano, his hometown that he never forgot, he personally founded the Asylum and the establishment of the local hospital. In Bellano Vitali was also involved in the construction of the male oratory, the realization of the parish library, the mutual aid and the professional schools; he also donated the land necessary for the enlargement of the municipal cemetery, with the realization of the new entrance where today there is a bronze statue that portrays him, by the sculptor Branca.
Monsignor Luigi Vitali died in Colico on November 6, 1919.